Spravato® Nasal Spray
Spravato® is an innovative treatment designed for individuals struggling with treatment-resistant depression (TRD) or depressive symptoms associated with major depressive disorder (MDD) with suicidal thoughts or actions. Unlike traditional antidepressants, Spravato® works on the glutamate pathway in the brain, offering a novel approach to alleviating severe depression. Patients self-administer the nasal spray under medical supervision to ensure safety and effectiveness.
At European Med-Beauty Family Clinic in Naperville, IL, Spravato® provides a new lifeline for individuals who haven’t responded to other antidepressants. With noticeable improvements often seen within a few weeks, this treatment offers faster relief while helping patients regain control of their mental health. Book a consultation today to explore how Spravato® can support your journey toward wellness.
What is Spravato® Therapy?
Spravato® (esketamine) is the first FDA-approved nasal spray for treatment-resistant depression and depressive symptoms in adults with suicidal thoughts. Unlike oral antidepressants, it targets the glutamate system in the brain to promote faster recovery. The treatment is paired with an oral antidepressant. It involves multiple weekly sessions during the initial phase, followed by fewer sessions as symptoms improve.
Spravato® must be administered in a certified healthcare setting under the Spravato® REMS program. Patients are monitored for two hours after each dose to manage potential side effects.
Benefits of Spravato® Nasal Spray:
- Targets the brain's glutamate pathway for faster symptom relief
- Provides rapid improvements within 4 weeks for many patients
- Reduces the likelihood of depressive relapse with continued use
- Helps manage treatment-resistant depression and MDD with suicidal thoughts
- Administered under medical supervision to ensure safety
- Minimal downtime with patients resuming daily activities after observation
- Customizable treatment schedules based on individual progress
- Effective for patients who have not responded to other antidepressants
- Supports long-term mental wellness when combined with oral antidepressants
- Reduces suicidal thoughts in patients with severe depression
Frequently Asked Questions
Spravato® works differently by targeting the glutamate pathway instead of serotonin or dopamine. This unique mechanism provides faster symptom relief compared to traditional oral antidepressants, which can take weeks or months to take effect.
During the first month, patients typically receive Spravato® twice a week. After that, the frequency is reduced to once a week or every two weeks, depending on individual progress and response.
You will administer the nasal spray yourself under the guidance of a healthcare provider. After taking the dose, you’ll be monitored for at least two hours to ensure no serious side effects, such as dizziness or sedation. A caregiver or family member must accompany you and drive you home after the session.
Spravato® may cause side effects such as dizziness, nausea, increased blood pressure, and dissociation (feeling disconnected). There is also a potential for misuse due to its esketamine component, which is related to ketamine. Patients are closely monitored to minimize these risks.
Yes, Spravato® is used in combination with oral antidepressants for maximum effectiveness. It may also complement psychotherapy and other mental health treatments, but always consult with your healthcare provider before making changes to your care plan.
Since Spravato® is an advanced treatment for severe depression, many insurance plans may cover part or all of the costs. However, coverage can vary, so it’s essential to check with your insurance provider beforehand. European Med-Beauty Family Clinic offers financing options to make the treatment more accessible if needed.